학술논문

A simple, diversity oriented synthesis of highly substituted pyridines.
Document Type
Article
Source
Journal of Heterocyclic Chemistry. Jul2011, Vol. 48 Issue 4, p792-798. 7p. 5 Diagrams, 2 Charts.
Subject
*PYRIDINE
*CONDENSATION
*NITRILES
*POTASSIUM compounds
*CANDIDA albicans
*ACIDS
Language
ISSN
0022-152X
Abstract
A particularly straightforward and efficient protocol for the synthesis of highly substituted pyridines, based on a condensation reaction of β-aminocrotonitrile and easily accessible ( E)-2-oxo-4-aryl-but-3-enoic acids and ( E)-4-oxo-4-aryl-but-2-enoic acids is described. J. Heterocyclic Chem., (2011). [ABSTRACT FROM AUTHOR]