학술논문

Panache: a web browser-based viewer for linearized pangenomes.
Document Type
Article
Source
Bioinformatics. 12/1/2021, Vol. 37 Issue 23, p4556-4558. 3p.
Subject
*REPRESENTATIONS of graphs
*VISUALIZATION
Language
ISSN
1367-4803
Abstract
Motivation Pangenomics evolved since its first applications on bacteria, extending from the study of genes for a given population to the study of all of its sequences available. While multiple methods are being developed to construct pangenomes in eukaryotic species there is still a gap for efficient and user-friendly visualization tools. Emerging graph representations come with their own challenges, and linearity remains a suitable option for user-friendliness. Results We introduce Panache, a tool for the visualization and exploration of linear representations of gene-based and sequence-based pangenomes. It uses a layout similar to genome browsers to display presence absence variations and additional tracks along a linear axis with a pangenomics perspective. Availability and implementation Panache is available at github.com/SouthGreenPlatform/panache under the MIT License. [ABSTRACT FROM AUTHOR]