학술논문
Testing guidelines for hereditary non-polyposis colorectal cancer.
Document Type
Review
Source
Subject
*COLON cancer prevention
*GENETIC disorders
*MICROSATELLITE repeats
*MOLECULAR diagnosis
*CHROMOSOMES
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Language
ISSN
1474-175X
Abstract
Hereditary non-polyposis colorectal cancer is almost always associated with microsatellite instability, so what is the best way to identify the disorder at an early-stage, and what should the next step be in preventing the development of colorectal cancer? Different clinical and molecular diagnostic guidelines have recently been proposed in the context of recent scientific advances, but how are these criteria interpreted and modified across the world? [ABSTRACT FROM AUTHOR]