부산대학교 도서관

This article discusses the synthesis of a hexasaccharide repeating unit found in the cell wall of Providencia alcalifaciens, a bacteria responsible for urinary tract infections and diarrheal diseases. The development of glycoconjugate-based therapeutics using this hexasaccharide could be useful in controlling these infections. The article presents a synthetic strategy for the preparation of the hexasaccharide, involving regio-selective glycosylation and the use of specific glycosylation promoters. The synthesis of various intermediates and their subsequent glycosylation steps are described in detail. The text also provides information about the synthesis and characterization of several compounds, including their yields and physical properties. Additionally, the text mentions the availability of supporting information, such as NMR spectra of the compounds. [Extracted from the article]