학술논문

Expeditious Synthesis of the Hexasaccharide Repeating Unit of the Capsular Polysaccharide of Streptococcus pneumoniae Type 7A.
Document Type
Article
Source
Synthesis. Apr2024, Vol. 56 Issue 7, p1139-1146. 8p.
Subject
*STREPTOCOCCUS pneumoniae
*GLYCOLS
*SCHOLARSHIPS
*STREPTOCOCCAL diseases
*AZIDO group
*DRUG discovery
*POLYSACCHARIDES
Language
ISSN
0039-7881
Abstract
This article discusses the development of a chemical synthesis strategy for the hexasaccharide repeating unit of the capsular polysaccharide of Streptococcus pneumoniae type 7A. The synthesis was achieved using a block synthetic strategy with minimal functional group modifications. The reactions were monitored by TLC and the products were characterized using NMR spectroscopy. The text provides detailed information about the synthesis and characterization of three compounds. The compounds mentioned in the text are complex and have multiple functional groups. The text provides information about the synthesis and characterization of a compound, including details about the chemical structure, NMR spectra, and HRMS data. The authors acknowledge the funding support they received for their research. [Extracted from the article]