학술논문

Determination of Sample Concentrations by PULCON NMR Spectroscopy.
Document Type
Article
Source
Australian Journal of Chemistry. 2022, Vol. 75 Issue 2, p160-164. 5p.
Subject
*BIOCHEMISTS
*BIOLOGICAL assay
*NUCLEAR magnetic resonance spectroscopy
*ANALYTICAL chemistry
*BIOCHEMISTRY
*PHARMACEUTICAL chemistry
Language
ISSN
0004-9425
Abstract
PULCON (Pulse Length-Based Concentration Determination) is a powerful, versatile, non-invasive, and accurate technique for measuring solution concentrations via routine NMR spectroscopy. It is particularly useful for preparing accurate solutions of compounds for biological assays, and avoids weight-based errors caused by contaminants (e.g. moisture). This article provides an introductory guide for biological and medicinal chemists, and highlights the diversity of applications. [ABSTRACT FROM AUTHOR]