학술논문
Multiple sclerosis risk genotypes correlate with an elevated cerebrospinal fluid level of the suggested prognostic marker CXCL13.
Document Type
Article
Author
Source
Subject
*MULTIPLE sclerosis
*CEREBROSPINAL fluid
*QUANTITATIVE research
*DISEASE susceptibility
*PATIENTS
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Language
ISSN
1352-4585
Abstract
The article presents a study which aims to investigate the variants genetic susceptibility in multiple sclerosis that was correlated to CXCL13 levels and presents to the cerebrospinal fluid (CSF) of MS patients. The study made use of an parametric methods for statistical analysis and PLINK v.1.07 software for wald test. The result of the study shows that increasing levels of CXCL13 was the genetic predisposition that correlates in MS patients with severity of disease.