학술논문

Thionucleotides as Inhibitors of Ribonucleotide Reductase.
Document Type
Article
Source
Nucleosides, Nucleotides & Nucleic Acids. May2003, Vol. 22 Issue 5-8, p883-885. 3p.
Subject
*NUCLEOTIDES
*CHEMICAL inhibitors
*SUGARS
*LYMPHOBLASTOID cell lines
*PYROPHOSPHATES
Language
ISSN
1525-7770
Abstract
Ribonucleosides and xylonucleosides bearing a disulfide function on the sugar ring were synthesized. Ribonucleosides belonging to the cytidine series were found to efficiently reduce dNTP pools in the human lymphoblastoïd CEM/SS cell line. [ABSTRACT FROM AUTHOR]