학술논문
Phototoxicity of strained Ru(ii) complexes: is it the metal complex or the dissociating ligand?
Document Type
Article
Author
Source
Subject
*RUTHENIUM compounds
*LIGANDS (Chemistry)
*ACUTE myeloid leukemia
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Language
ISSN
1477-9226
Abstract
A photochemically dissociating ligand in Ru(bpy)2(dmphen)Cl2 [bpy = 2,2′-bipyridine; dmphen = 2,9-dimethyl-1,10-phenanthroline] was found to be more cytotoxic on the ML-2 Acute Myeloid Leukemia cell line than Ru(bpy)2(H2O)22+ and prototypical cisplatin. Our findings illustrate the potential potency of diimine ligands in photoactivatable Ru(ii) complexes. [ABSTRACT FROM AUTHOR]