부산대학교 도서관

BACKGROUND: There are many benefits associated with the laparoscopic surgery including faster recovery, shorter hospital stay and prompt return to normal activities. Although laparoscopic surgery is minimally invasive in nature but high incidence of postoperative nausea and vomiting (PONV) remains a major cause of morbidity. To prevent PONV, multimodal techniques are helpful, but not any one technique is idea to deal with this problem. This study was carried out to compare the efficacy of intraoperative high oxygen concentration in prevention of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy. OBJETCIVES: The objective of this study is to observe the effectiveness of high oxygen concentration in prevention of postoperative nausea and/ or vomiting in adult females undergoing elective laparoscopic cholecystectomy. Patients were observed for 24 hours postoperatively for nausea and vomiting. High oxygen will be considered effective, if no nausea or vomiting occurred in the 24hrs period. METHODS: This study was conducted in the Department of Anesthesiology at Aga Khan University and Hospital, Karachi from June 2013 to May 2014.Design of the study was Prospective observational study 74 ASA I and II adult female patients undergoing elective laparoscopic cholecystectomy were included in this study. All the patients who fulfill the inclusion criteria were included in this study. Postoperatively patients were observed for 24 hours for any episode of nausea or vomiting, or whether the patients required any rescue antiemetic. RESULTS: High intraoperative oxygen concentration has not significantly affected the incidence of PONV in adult female patients underwent laparoscopic cholecystectomy. During the 24 hr period, out of 74 patients, 30patients (40.54%) experience PONV and required rescue antiemetic medication and 44 patients (59.46) experience no PONV. CONCLUSION: This study has demonstrated that high intraoperative oxygen was not effective in prevention of postoperative nausea and vomiting in adult female patients undergoing elective laparoscopic surgery. [ABSTRACT FROM AUTHOR]