부산대학교 도서관

AIM: 1. To determine the prevalence of cognitive deficits in hypertensive patients 2. To compare cognitive deficit in patients with and without hypertension. MATERIAL AND METHODS: A comparative cross sectional observational study including patients already diagnosed with hypertension according to JNC VIII criteria between the ages of 45 to 60 years. Cognitive function assessment was done by two tests Addenbrooke's cognitive examination score and Trail Making Test A and B. RESULTS: The average age was 53.57 ± 4.94 for cases and 53.04 ± 5.03 for controls. The mean Systolic Blood Pressure in cases is 136.56 ± 12.31and in controls is 114.44 ± 6.218 and mean Diastolic Blood Pressure in cases is 87.91 ± 7.29 and 72.59± 6.10 in controls. While 62 cases had scores below 82, 49 controls had similar scores. The mean time taken by the cases to complete TMT Part A was 94.27 ± 15.34 seconds while controls took lesser time of 68.00 ± 12.97 seconds and to complete TMT Part B was 207.17 ± 44.98 seconds while controls took lesser time of 163.67 ± 33.51 seconds. CONCLUSION: High prevalence of cognitive impairment was found in hypertensive patients as compared to normotensives. Lower scores on Addenbrooke's score were seen among the hypertensive group compared to normotensive control. Time taken by the normotensive control group to complete trail making test part A and part B was shorter than the time taken by hypertensive cases. Hypertension has been a risk factor for cognitive dysfunction in the patients in the age group of 45-60 years in our study. [ABSTRACT FROM AUTHOR]