부산대학교 도서관

We believe that our discovery was an incidental finding especially as the tumoural cells didn't show any loss of expression of MMR proteins, and this despite the fact that our tumour presents certain characteristics of MMR-deficient breast cancers (high grade, high mitotic index, triple negative phenotype). This case highlights two points: first, a germline mutation is not necessarily involved in a given carcinogenesis and second, as cancer predisposition syndromes are not uncommon, and as genetic testing use increases, the incidental discovery of these syndromes will be more and more frequent, requiring appropriate management and interpretation. Keywords: adenomyoepihtelioma; lynch syndrome EN adenomyoepihtelioma lynch syndrome 572 575 4 07/04/23 20230801 NES 230801 We report a case of a malignant adenomyoepithelioma in a 46-year-old woman with a significant family history of cancer. [Extracted from the article]