학술논문
A Concise Synthesis of Sacidumlignan B.
Document Type
Article
Author
Source
Subject
*NATURAL products
*BARBIER reactions
*KETONES
*RING formation (Chemistry)
*AMINATION
*SKELETON
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*
*
*
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Language
ISSN
1420-3049
Abstract
A short synthesis of racemic Sacidumlignan B was achieved for the first time. The key steps included a formal reductive coupling between the diaryl ketone and the crotyl bromide, and the subsequent Friedel–Crafts cyclization, which led to an efficient construction of dihydronaphthalene skeleton in this 2,7′-cyclolignan natural product. [ABSTRACT FROM AUTHOR]