학술논문

SEBACEOUS GLAND SECRETION IN PARKINSON'S DISEASE DURING L-DOPA TREATMENT.
Document Type
Article
Source
Journal of Investigative Dermatology. Mar73, Vol. 60 Issue 3, p134-136. 3p.
Subject
*SEBUM
*SEBACEOUS glands
*DOPA
*PHENYLALANINE
*EXOCRINE secretions
*PARKINSON'S disease
Language
ISSN
0022-202X
Abstract
Sebum production was measured on the foreheads of 21 patients with Parkinson's disease before and during long-term L-dopa treatment. A statistically significant decrease in the amount of sebum was demonstrable during treatment although considerable variation in responsiveness was observed. No correlation between the dose of L-dopa and the degree of sebaceous gland inhibition could be established. The quantitative reduction of sebum could not be related to the degree of neurologic improvement. [ABSTRACT FROM AUTHOR]