부산대학교 도서관

A novel reaction condition has been developed for the synthesis of unsymmetrical glycosyl diselenide derivatives in excellent yield by the reaction of glycosyl selenocyanates as selenol surrogates with symmetrical diselenides in the presence of hydrazine monohydrate at room temperature. The reaction metal-free condition is reasonably fast, simple, non-malodorous and suitable for scale-up. [Display omitted] • Unsymmetrical glycosyl diselenides were prepared by nucleophilic addition of selenols to diselenides. • Non-anomerically linked alkyl glycosyl diselenides were synthesized. • Glycosyl selenocyanates were hydrolyzed into selenolates by hydrazine monohydrate. • Glycosyl selenocyanates were used as glycosyl selenol surrogates. • All reactions were simple, high yielding and suitable for scaling up. [ABSTRACT FROM AUTHOR]