학술논문

Kleisins: A Superfamily of Bacterial and Eukaryotic SMC Protein Partners
Document Type
Letter
Source
Molecular Cell. Mar2003, Vol. 11 Issue 3, p571. 5p.
Subject
*PROTEINS
*EUKARYOTIC cells
Language
ISSN
1097-2765
Abstract
We describe a superfamily of eukaryotic and prokaryotic proteins (kleisins) that includes ScpA, Scc1, Rec8, and Barren. Scc1 interacts with SMC proteins through N- and C-terminal domains to form a ring-like structure. Since these are the only domains conserved among kleisins, we suggest that ring formation with SMC proteins may define this family. [Copyright &y& Elsevier]