학술논문
Novel Denisovan and Neanderthal Retroviruses.
Document Type
Article
Author
Source
Subject
*DENISOVANS
*RETROVIRUS genetics
*HOMINIDS
*HUMAN endogenous retroviruses
*HUMAN genome
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Language
ISSN
0022-538X
Abstract
Following the recent availability of high-coverage genomes for Denisovan and Neanderthal hominids, we conducted a screen for endogenized retroviruses, identifying six novel, previously unreported HERV-K(HML2) elements (HERV-K is human endogenous retrovirus K). These elements are absent from the human genome (hg38) and appear to be unique to archaic hominids. These findings provide further evidence supporting the recent activity of the HERV-K(HML2) group, which has been implicated in human disease. They will also provide insights into the evolution of archaic hominids. [ABSTRACT FROM AUTHOR]