부산대학교 도서관

• We presented a new perspective for the qualitative and semi-quantitative analysis of TiO 2 oxides phase concentration. • For the first time, we applied Raman imaging to determine phase distribution and estimated rutile/anatase concentration in TiO 2 thin layers. • Rutile and anatase phase mixture has beneficial properties to create a permanent tissue-implant connection. • We evaluated the distribution of TiO 2 layer components using K-means Cluster Analysis (KMC) and calculations bands' relative intensity. • We demonstrated the advantages of Raman imaging in calculating the surface composition essential for biomaterials surface preparation and evaluation. The paper presents research on estimating concentrations and distribution of rutile and anatase on the surface and cross-section of TiO 2 thin layers by Raman imaging. The TiO 2 layers were formed by hybrid oxidation, which combines fluidised bed (FB) diffusive treatment at 640 °C for 8 h and magnetron sputtering. The rutile structure of the titania layer plays a vital role in biomaterials surface, inducing the apatite deposition depending on the lattice matching between rutile and apatite. However, a mixture of rutile and anatase has also been shown to have beneficial properties in terms of biomedical applications. According to this statement, the critical point is to estimate the rutile/anatase phase ratio in order to optimise the substrate preparation method to obtain the most favourable surface to create a permanent tissue-implant connection. The aforementioned phase composition is created during the proposed double-step synthesis of hybrid TiO 2 layer by FB (rutile) and physical vapour deposition (PVD, rutile/anatase). In this work, scanning electron microscopy assisted with energy dispersive spectroscopy (SEM-EDS) was used for microstructural characterisation and elemental analysis. Moreover, Raman imaging was applied to determine phase distribution and estimate rutile/anatase concentration in TiO 2 thin layers. Such an approach proposed by the authors presents new perspectives for the qualitative and semi-quantitative analysis of the TiO 2 oxide phase concentration. It also demonstrates the significant potential of the Raman imaging technique for calculating surface composition determining homogeneity of the coating to evaluate material to obtain the best possible proportion of TiO 2 phases, ideal for biomedical applications. [Display omitted] [ABSTRACT FROM AUTHOR]