학술논문
Genetic mutations in adipose triglyceride lipase and myocardial up-regulation of peroxisome proliferated activated receptor-γ in patients with triglyceride deposit cardiomyovasculopathy.
Document Type
Article
Author
Hirano, Ken-ichi; Tanaka, Tatsuya; Ikeda, Yoshihiko; Yamaguchi, Satoshi; Zaima, Nobuhiro; Kobayashi, Kazuhiro; Suzuki, Akira; Sakata, Yasuhiko; Sakata, Yasushi; Kobayashi, Kunihisa; Toda, Tatsushi; Fukushima, Norihide; Ishibashi-Ueda, Hatsue; Tavian, Daniela; Nagasaka, Hironori; Hui, Shu-Ping; Chiba, Hitoshi; Sawa, Yoshiki; Hori, Masatsugu
Source
Subject
*GENETIC mutation
*ADIPOSE tissues
*TRIGLYCERIDES
*LIPASES
*PEROXISOME proliferator-activated receptors
*CARDIOMYOPATHIES
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Language
ISSN
0006-291X
Abstract
Highlights: [•] Triglyceride deposit cardiomyovasculopathy (TGCV) is a rare severe heart disease. [•] PPARγ is up-regulated in myocardium in patients with TGCV. [•] Possible vicious cycle for fatty acid may be involved in pathophysiology of TGCV. [Copyright &y& Elsevier]