학술논문
The Intensive Care Medicine research agenda on critically ill oncology and hematology patients.
Document Type
Journal Article
Author
Azoulay, Elie; Schellongowski, Peter; Darmon, Michael; Bauer, Philippe; Benoit, Dominique; Depuydt, Pieter; Divatia, Jigeeshu; Lemiale, Virginie; Vliet, Maarten; Meert, Anne-Pascale; Mokart, Djamel; Pastores, Stephen; Perner, Anders; Pène, Frédéric; Pickkers, Peter; Puxty, Kathryn; Vincent, Francois; Salluh, Jorge; Soubani, Ayman; Antonelli, Massimo
Source
Subject
*HEMATOLOGICAL oncology
*INTENSIVE care units
*CANCER patients
*HEMATOPOIETIC stem cell transplantation
*CRITICALLY ill
*SEPTIC shock treatment
*HEMODYNAMICS
*CANCER chemotherapy
*THERAPEUTICS
*SEPTICEMIA treatment
*TUMOR treatment
*ACUTE kidney failure
*ANTINEOPLASTIC agents
*CATASTROPHIC illness
*CRITICAL care medicine
*HEMATOLOGY
*HOSPITAL admission & discharge
*MEDICAL quality control
*MEDICAL research
*ONCOLOGY
*HEALTH outcome assessment
*PALLIATIVE treatment
*PATIENTS
*QUALITY of life
*RESPIRATORY insufficiency
*SEPSIS
*TUMORS
*DISEASE complications
*DIAGNOSIS
TREATMENT of acute kidney failure
RESPIRATORY insufficiency treatment
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
Language
ISSN
0342-4642
Abstract
Over the coming years, accelerating progress against cancer will be associated with an increased number of patients who require life-sustaining therapies for infectious or toxic chemotherapy-related events. Major changes include increased number of cancer patients admitted to the ICU with full-code status or for time-limited trials, increased survival and quality of life in ICU survivors, changing prognostic factors, early ICU admission for optimal monitoring, and use of noninvasive diagnostic and therapeutic strategies. In this review, experts in the management of critically ill cancer patients highlight recent changes in the use and the results of intensive care in patients with malignancies. They seek to put forward a standard of care for the management of these patients and highlight important updates that are required to care for them. The research agenda they suggest includes important studies to be conducted in the next few years to increase our understanding of organ dysfunction in this population and to improve our ability to appropriately use life-saving therapies or select new therapeutic approaches that are likely to improve outcomes. This review aims to provide more guidance for the daily management of patients with cancer, in whom outcomes are constantly improving, as is our global ability to fight against what is becoming the leading cause of mortality in industrialized and non-industrialized countries. [ABSTRACT FROM AUTHOR]