학술논문

Association of idiopathic venous thromboembolism with single point-mutation at Arg506 of factor V.
Document Type
Article
Source
Lancet. 6/18/1994, Vol. 343 Issue 8912, p1535. 2p. 2 Black and White Photographs, 1 Graph.
Subject
*THROMBOEMBOLISM
*PROTEIN C
*BLOOD coagulation factors
Language
ISSN
0140-6736
Abstract
Analyzes patients with documented idiopathic thromboembolism for the occurrence of point mutations within the activated protein C (APC) sensitive regions of blood coagulation factor V. Association of venous thromboembolism with molecular defects in several hemostatic components; Anticoagulant response to APC; Implications of the high frequency of APC resistance.