학술논문
Complete remission of sclerodermatous cutaneous graft‐versus‐host disease after low‐dose interleukine‐2 treatment.
Document Type
Article
Author
Source
Subject
*GRAFT versus host disease
*SKIN diseases
*INTERLEUKIN-2
*SUPPRESSOR cells
*IMMUNOLOGIC diseases
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Language
ISSN
0926-9959
Abstract
Graft-versus-host disease (GVHD) is an immunological reaction, frequently complicating allogeneic hemopoietic stem cell transplantation, that can involve many organs with a wide range of clinical presentations. We report the case of a dramatic improvement of sclerodermatous cGVHD in a 28-year-old patient after 8 weeks of daily low-dose subcutaneous interleukine-2 treatment. 1b). low-dose interleukine-2 treatment gradually improved skin sclerosis (one-third improvement at 3 months, half improvement at 6 months and complete resolution of skin symptoms at 1 year). [Extracted from the article]