부산대학교 도서관

Introduction: Declining trends in stroke mortality have been observed in Norway since the 1970s. National trends of stroke incidence are lacking. Aims: To describe national time trends in incidence of fatal and non-fatal ischemic stroke, haemorrhagic stroke, subarachnoid bleeding and unspecified stroke in the period 2001-2014, by sex and age group. Methods: National hospital discharge diagnoses in the CVDNOR database and in the National Patient registry were linked to the National Cause of Death Registry. All hospitalizations with stroke as main or secondary diagnosis and out-of-hospital deaths with stroke as underlying cause for individuals = 25 years were obtained during 1994-2014. Incident stroke was defined as hospitalization or out-of-hospital-death due to stroke with no prior hospitalization for stroke or stroke sequela during the previous seven years. Incidence rate ratios were estimated by Poisson regression analyses. We used direct standardization against the 2001 Norwegian population. Preliminary analyses of change in incidence rates over time are presented. Results: During 2001 to 2014 the number of incident total stroke cases declined from 12,137 to 10,166. The proportion due to out-of-hospital deaths declined from 10% to 7%. Of total stroke cases in 2014, 73% were ischemic, 14% haemorrhagic, 5% subarachnoid haemorrhages and 8% unspecified strokes. The age-standardized incidence of total stroke declined from 324 to 232 per 100 000 person years among men and from 234 to 163 among women. In individuals 45-84 years, incidence rates of total, ischemic and haemorrhagic stroke declined. Incidence rates in the age group 85 + years declined for total and ischemic stroke, but increased for haemorrhagic strokes in men and did not change significantly in women. In the youngest age group 25-44 years, incidence rates of total and haemorrhagic stroke did not change significantly, and for ischemic stroke incidence rates increased in men and did not change significantly in women. Conclusions: The total stroke incidence rates decreased from 2001 to 2014 in the Norwegian population 45 years and older. Increased incidence rates of haemorrhagic stroke in men 85 + years and of ischemic stroke in men below 45 years needs further investigation. [ABSTRACT FROM AUTHOR]