학술논문
West Nile Virus RNA Not Detected in Urine of 40 People Tested 6 Years After Acute West Nile Virus Disease.
Document Type
Article
Author
Source
Subject
*WEST Nile virus
*IMMUNE response
*VIREMIA
*POLYMERASE chain reaction
*DNA polymerases
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Language
ISSN
0022-1899
Abstract
West Nile virus (WNV) causes an acute infection that is usually cleared by an effective immune response after several days of viremia. However, a recent study detected WNV RNA in the urine of 5 of 25 persons (20%) tested several years after their initial acute WNV disease. We evaluated an established cohort of 40 persons >6 years after initial infection with WNV. Urine collected from all participants tested negative for WNV RNA by reverse-transcription polymerase chain reaction and transcription-mediated amplification. Prospective studies are needed to determine if and for how long WNV persists in urine following WNV disease. [ABSTRACT FROM AUTHOR]