학술논문

Tactile stimulation and neonatal isolation affect behavior and oxidative status linked to cocaine administration in young rats.
Document Type
Article
Source
Behavioural Processes. Mar2014, Vol. 103, p297-305. 9p.
Subject
*TOUCH
*STIMULUS & response (Biology)
*COCAINE abuse
*DRUG administration
*LABORATORY rats
*CATALASE
*OXIDATION of proteins
Language
ISSN
0376-6357
Abstract
Highlights: [•] Early tactile stimulation (TS) reduced cocaine-place preference in young rats. [•] TS and neonatal isolation (10min – NI10) reduced anxiety-like behavior in rats. [•] TS exposure increased catalase activity in brain of cocaine-treated rats. [•] NI (60min – NI60) increased protein oxidation in brain of cocaine-treated rats. [•] Neonatal handling may change preference behavior for abuse drugs. [ABSTRACT FROM AUTHOR]