학술논문
Flaxseed flour (Linum usitatissinum) consumption improves bone quality and decreases the adipocyte area of lactating rats in the post-weaning period.
Document Type
Journal Article
Author
Ribeiro, Danielle Cavalcante; Pereira, Aline D'Avila; da Silva, Paula Cristina Alves; dos Santos, Aline de Sousa; Santana, Fernanda Carvalho de; Boueri, Bianca Ferolla da Camara; Pessanha, Carolina Ribeiro; Abreu, Maíra Duque Coutinho de; Mancini-Filho, Jorge; da Silva, Eduardo Moreira; Nascimento-Saba, Celly Cristina Alves do; da Costa, Carlos Alberto Soares; Boaventura, Gilson Teles
Source
Subject
*LINUM
*FOOD consumption
*BONE physiology
*FAT cells
*LACTATION
*LABORATORY rats
*PREVENTION of obesity
*OSTEOPOROSIS prevention
*ADIPOSE tissues
*ANIMAL experimentation
*ARACHIDONIC acid
*DIET
*FATTY acids
*FEMUR
*FLAXSEED
*FOOD
*INFANT weaning
*OBESITY
*OSTEOPOROSIS
*RATS
*SEEDS
*UNSATURATED fatty acids
*BONE density
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Language
ISSN
0963-7486
Abstract
The aim of this work was to evaluate the effects of flaxseed flour in the intake on adiposity and femur structure of the lactating rats during the post-weaning period. After weaning, the lactating rats were divided into control (C,n = 6) and experimental (F,n = 6) groups treated with a diet containing flaxseed flour. Serum hormone and fatty acids composition, morphology of intra-abdominal adipocytes, computed tomography and biomechanical analyses of femur were determined. Food intake, body mass and hormone analysis have shown similar results. The F group showed the following (p < 0.05): lower arachidonic acid (–60%), total polyunsaturated fatty acids (–30%) and retroperitoneal adipocytes (–36%) area. Higher radiodensity of femoral head region (+29%) and higher maximum force (+18%), breaking strength (+18%) and rigidity (+31%). Fatty acid composition of flaxseed flour decreased the area of adipocytes and improved the bone quality, which may be associated with lower serum levels of arachidonic acid levels, during the post-weaning period. [ABSTRACT FROM PUBLISHER]