부산대학교 도서관

Introduction: the pancreas is a glandular organ of dual composition with both exocrine and endocrine components. Tumors of exocrine pancreas are rare with more than 95% being malignant. Methods & materials: this is a retrospective clinico-histopathological study of 61 cases registered in our institute from Feb 2016 to Dec 2018. The details of patients were retrieved from patients' files. Information retrieved included sociodemographic data, clinical presentation, anatomical site, gross appearance, tumor stage, histopathological type and grade, presence of metastasis. Results: during the study period, a total of 61 malignancies were registered. Of these, 23 (37%) were histopathologically confirmed pancreatic cancer. The diagnosis in the remaining 38 patients was based on clinical and radiological basis. Male to female ratio of 1.4:1. The age ranged from 40 to 90 years with a median age of 64 years. Forty nine patients (80%) presented with abdominal pain, 13 patients (21%) were jaundiced. The head was the most frequent site for pancreatic tumor in 48 (54%) cases followed by tail, body. Adenocarcinoma was the most common histopathological tumor in 43(90%) patients. Thirty (33.7%) patients were presented in locally advanced stages and 54 (60.6 %) patients had metastasis. Conclusion: the study was limited by being a retrospective, a relatively small number of patients and representing the experience of a single cancer institute, therefore, larger prospective studies are recommended to study the clinicodemografic character of this disease in the country. [ABSTRACT FROM AUTHOR]