학술논문

Smart nanoparticles and microbeads for interventional embolization therapy of liver cancer: state of the art.
Document Type
Article
Source
Journal of Nanobiotechnology. 2/6/2023, Vol. 21 Issue 1, p1-12. 12p.
Subject
*LIVER cancer
*CANCER treatment
*MICROBEADS
*CHEMOEMBOLIZATION
*NANOMEDICINE
*HEPATOCELLULAR carcinoma
*SMART materials
Language
ISSN
1477-3155
Abstract
The process of transcatheter arterial chemoembolization is characterized by the ability to accurately deliver chemotherapy drugs with minimal systemic side effects and has become the standard treatment for unresectable intermediate hepatocellular carcinoma (HCC). However, this treatment option still has much room for improvement, one of which may be the introduction of nanomaterials, which exhibit unique functions and can be applied to in vivo tumor imaging and therapy. Several biodegradable and multifunctional nanomaterials and nanobeads have recently been developed and applied in the locoregional treatment of hepatocellular cancer. This review explores recent developments and findings in relation to micro-nano medicines in transarterial therapy for HCC, emerging strategies to improve the efficacy of delivering nano-based medicines, and expounding prospects for clinical applications of nanomaterials. [ABSTRACT FROM AUTHOR]