학술논문
Acute severe pulmonary hypertension during weaning from cardiopulmonary bypass for aortic valve replacement surgery: A case report.
Document Type
Article
Author
Source
Subject
*VASODILATORS
*RESEARCH funding
*SUFENTANIL
*CARDIOPULMONARY bypass
*AORTIC stenosis
*ARTIFICIAL respiration
*PULMONARY arterial hypertension
*VENTILATOR weaning
*VASOCONSTRICTORS
*ECHOCARDIOGRAPHY
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Language
ISSN
0267-6591
Abstract
Pulmonary arterial pressure (PAH) usually increases after cardiopulmonary bypass (CPB), but this normally does not affect weaning off CPB. Here we report a case of severe PAH in a patient with normal left atrial pressure. Prolonging CPB by 45 min did not lead to lower PAH. Given that lung injury can stimulate secretion of vasoconstrictors that trigger PAH, we decided to gradually increase blood flow into the lungs in an effort to restore the balance between pulmonary vasoconstrictors and vasodilators. Pulmonary artery pressure gradually decreased, allowing the patient to be weaned off CPB, after which she recovered uneventfully. Our experience suggests an approach for managing acute, severe PAH after CPB without the need for mechanical circulatory support. [ABSTRACT FROM AUTHOR]