학술논문

Ancestry matters: Building inclusivity into preclinical study design.
Document Type
Article
Source
Cell. May2021, Vol. 184 Issue 10, p2525-2531. 7p.
Subject
*EXPERIMENTAL design
*GENEALOGY
*CELL lines
*INDIVIDUALIZED medicine
Language
ISSN
0092-8674
Abstract
Human cell lines (CLs) are key assets for biomedicine but lack ancestral diversity. Here, we explore why genetic diversity among cell-based models is essential for making preclinical research more equitable and widely translatable. We lay out practical actions that can be taken to improve inclusivity in study design. [ABSTRACT FROM AUTHOR]