학술논문

Asperpenes D and E from the fungus Aspergillus sp. SCS-KFD66 isolated from a bivalve mollusk, Sanguinolaria chinensis.
Document Type
Article
Source
Journal of Asian Natural Products Research. Feb2021, Vol. 23 Issue 2, p117-122. 6p.
Subject
*ASPERGILLUS
*BIOLOGICAL products
*CARBOXYLIC acids
*ENZYME inhibitors
*GLYCOSIDASES
*MOLECULAR structure
*MOLLUSKS
*SHELLFISH
*SKELETON
*SPECTRUM analysis
*FREE radical scavengers
Language
ISSN
1028-6020
Abstract
Two new compounds named asperpenes D (1) and E (2) were isolated from the marine-derived fungus Aspergillus sp. SCS-KFD66. Their structures were determined on the basis of spectroscopic methods. Compound 2 represents the first natural product bearing a 2-substituted-5-oxo-4-phenyl-2,5-dihydrofuran-3-carboxylic acid skeleton. All the compounds were tested for enzyme inhibitory activity against AChE and α-glucosidase and DPPH radical scavenging activity, respectively. [ABSTRACT FROM AUTHOR]