학술논문

The Role of the DRY Motif of Human MC4R for Receptor Activation.
Document Type
Article
Source
Bioscience, Biotechnology & Biochemistry. Jun2004, Vol. 68 Issue 6, p1369-1371. 3p. 2 Diagrams.
Subject
*CORTIN
*CIRCULAR DNA
*HORMONE receptors
*MUTAGENESIS
*ANIMAL experimentation
*RESEARCH
Language
ISSN
0916-8451
Abstract
Studies mutant human MC4R circular DNAs by researchers from Japan. Role of the DRY motif of human MC4R for receptor activation; Construction of mutant human MC4R cDNAs by site directed mutagenesis; Elucidation on the involvement of melanocortins in anxiogenic-like behavior in experimental animals.