학술논문
Tailorable optical properties of polymer nanodots for triple-mode fluorescence detection of nucleic acids.
Document Type
Article
Source
Subject
*FLUORESCENCE resonance energy transfer
*OPTICAL properties
*NANODOTS
*DNA analysis
*NUCLEIC acids
*FLUORESCENCE anisotropy
*POLYMERS
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Language
ISSN
1359-7345
Abstract
We present a triple-mode nanosensor platform for nucleic acid detection utilizing fluorescence anisotropy and Förster resonance energy transfer (FRET) strategies. The self-assembled nanoprobes serve as mass amplifiers, nanoquenchers, or nanodonors, exhibiting high FRET efficiencies (64.4–86.5%) and demonstrating excellent detection capabilities in DNA and microRNA analysis. [ABSTRACT FROM AUTHOR]