학술논문
Induction of the zebrafish ventral brain floorplate requires cyclops/nodal signalling.
Document Type
Article
Author
Source
Subject
*ZEBRA danio
*CYCLOPS (Crustaceans)
*TRANSFORMING growth factors-beta
*GASTRULATION
*ANATOMY
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Language
ISSN
0028-0836
Abstract
Reports that cyc (cyclops), in the zebrafish, encodes a transforming growth factor-beta (TGF-beta)-related intercellular signalling molecule that is similar to mouse nodal. How cyc is expressed in dorsal medendoderm at gastrulation and in the prechordal plate until early somitogenesis; Details of results indicating that cyc provides essential non-cell autonomous signal at gastrulation leading to induction of the floorplate and ventral brain.