학술논문

Negative Affect Shared with Siblings is Associated with Structural Brain Network Efficiency and Loneliness in Adolescents.
Document Type
Article
Source
Neuroscience. 11/21/2019, Vol. 421, p39-47. 9p.
Subject
*LONELINESS
*AFFECT (Psychology)
*LARGE-scale brain networks
*TEENAGERS
*MENTAL depression
*SIBLINGS
Language
ISSN
0306-4522
Abstract
• Sibling-average positive affect is negatively associated with local network efficiency. • Sibling-average negative affect is positively associated with global and local network efficiency. • Network efficiency negatively mediates the association between sibling-average negative affect and loneliness. Loneliness has a strong neurobiological basis reflected by its specific relationships with structural brain connectivity. Critically, affect traits are highly related to loneliness, which shows close association with the onset and severity of major depressive disorder. This diffusion imaging study was conducted on a sample of adolescent siblings to examine whether positive and negative affect traits were related to loneliness, with brain network efficiency playing a mediating role. The findings of this study confirmed that both global and average local efficiency negatively mediated the association between low positive affect and high negative affect and loneliness, and the mediation was more sensitive to sibling-shared affect traits. The findings have important implications for interventions targeted at reducing the detrimental impact of familiar negative emotional experiences and loneliness. [ABSTRACT FROM AUTHOR]