학술논문

T-oligo as an anticancer agent in colorectal cancer.
Document Type
Article
Source
Biochemical & Biophysical Research Communications. Apr2014, Vol. 446 Issue 2, p596-601. 6p.
Subject
*T cells
*ANTINEOPLASTIC agents
*COLON cancer
*APOPTOSIS
*CELLULAR aging
*CELL differentiation
*EPIDERMAL growth factor receptors
Language
ISSN
0006-291X
Abstract
Highlights: [•] T-oligo induces cell cycle arrest, senescence, apoptosis, and differentiation in CRC. [•] Treatment with T-oligo downregulates telomere-associated proteins. [•] T-oligo combined with an EGFR-TKI additively inhibits cellular proliferation. [•] T-oligo has potential as an effective therapeutic agent for CRC. [ABSTRACT FROM AUTHOR]