학술논문
SYNTHESIS AND BIOLOGICAL ACTIVITIES OF (Z) AND (E) α-ETHENYL ACYCLONUCLEOSIDES.
Document Type
Article
Author
Source
Subject
*BIOSYNTHESIS
*NUCLEOSIDES
*DNA
*RNA
*VIRUSES
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*
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Language
ISSN
1525-7770
Abstract
Synthesis of Z and E ethenyl acyclonucleosides (6a-e and 7a-e) via Michael addition of nucleobases with the diethyl acetylenedicarboxylate is described. The structures of compounds have been confirmed by spectral data. New compounds were found to be inactive against DNA and RNA viruses. [ABSTRACT FROM AUTHOR]