학술논문
The Enigma of 2-Cys Peroxiredoxins: What Are Their Roles?
Document Type
Article
Source
Subject
*PEROXIREDOXINS
*RIDDLES
*TRANSLATIONAL research
*
*
Language
ISSN
0006-2979
Abstract
2-Cys peroxiredoxins are abundant thiol proteins that react efficiently with a wide range of peroxides. Unlike other enzymes, their exceptionally high reactivity does not rely on cofactors. The mechanism of oxidation and reduction of peroxiredoxins places them in a good position to act as antioxidants as well as key players in redox signaling. Understanding of the intimate details of peroxiredoxin functioning is important for translational research. [ABSTRACT FROM AUTHOR]