학술논문

Can Population Differences Explain the Contrasting Results of the Mwanza, Rakai, and Masaka HIV/Sexually Transmitted Disease Intervention Trials?
Document Type
Article
Source
JAIDS: Journal of Acquired Immune Deficiency Syndromes. 12/1/2004, Vol. 37 Issue 4, p1500-1513. 14p. 2 Charts, 6 Graphs.
Subject
*HIV infection transmission
*HIV infections
*SEXUALLY transmitted diseases
*COMMUNICABLE diseases
*POPULATION
SOCIAL aspects
Language
ISSN
1525-4135
Abstract
Determines whether population differences can explain the contrasting impact on HIV observed in the Mwanza trial of sexually transmitted disease (STD) syndromic treatment, the Rakai trial of STD mass treatment (MT) and the Masaka trial of information, education and communication with and without ST. Prediction of the effectiveness of each intervention strategy in each population; Observation that the baseline trial populations could be simulated by assuming higher risk behavior in Uganda compared with Mwanza in the 1980s; Finding that the projected HIV impacts were larger for the ST intervention in Mwanza than for the MT intervention in Rakai or the IEC and IEC plus St interventions in Masaka.