학술논문
Factors Influencing the Incubation of an Infectious Form of Creutzfeldt-Jakob Disease.
Document Type
Article
Author
Source
Subject
*AGE distribution
*INFECTIOUS disease transmission
*CREUTZFELDT-Jakob disease
*GENETICS
*PRIONS
*TIME
*HUMAN growth hormone
*DISEASE risk factors
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Language
ISSN
1058-4838
Abstract
The French epidemics of iatrogenic Creutzfeldt-Jakob disease after growth hormone (GH) treatment provide an opportunity to understand factors governing the inter-human transmission of prions. The present analysis relying on truncated Weibull distribution supports a relationship between host genetics, dose of the at-risk GH, age at treatment onset, and duration of the incubation period. [ABSTRACT FROM AUTHOR]