학술논문

Antithyroid drugs and release of inflammatory mediators by complement-attacked thyroid cells.
Document Type
Article
Source
Lancet. 9/12/1992, Vol. 340 Issue 8820, p633. 4p. 1 Chart, 5 Graphs.
Subject
*THYROID diseases
Language
ISSN
0140-6736
Abstract
States that thyroid cells are exposed to complement attack in Graves' disease and Hashimoto's thyroiditis, but are resistant to killing by homologous complement. Examines the effects of sublethal complement attack on thyroid cells in vitro; Results which suggest that sublethal complement attack in autoimmune thyroid diseases exacerbates tissue injury by causing thyroid cells to release potent phlogistic mediators; Details.