학술논문

The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections.
Document Type
Article
Source
PLoS Neglected Tropical Diseases. 9/15/2016, Vol. 10 Issue 9, p1-12. 12p.
Subject
*HELMINTHIASIS
*PARASITIC diseases
*NECATOR americanus
*AUTOIMMUNE diseases
*IMMUNOLOGIC diseases
*DISEASE risk factors
Language
ISSN
1935-2727
Abstract
Author Summary: Current iterations of the hygiene hypothesis suggest an adaptive role for helminth parasites in shaping the proper maturation of the immune system. However, aspects of this hypothesis are based on assumptions that may not fully account for realities about human helminth infections. Such realities include evidence of causal associations between helminth infections and asthma or inflammatory bowel disease as well as the fact that helminth infections remain widespread in the United States, especially among populations at greatest risk for inflammatory and autoimmune diseases. [ABSTRACT FROM AUTHOR]