학술논문

Multiple-site decontamination regimen without systemic antibiotics associated with reduced mortality in intubated patients.
Document Type
Letter
Source
Infectious Diseases. Jul2020, Vol. 52 Issue 7, p513-516. 4p. 1 Chart, 1 Graph.
Subject
*ANTIBIOTICS
*MORTALITY
*MULTIDRUG resistance in bacteria
*RESPIRATORY infections
*ANTIBIOTIC prophylaxis
*INFECTION prevention
*BRONCHOALVEOLAR lavage
Language
ISSN
2374-4235
Abstract
In this study conducted in ICUs with low-level antimicrobial resistance, the use of a selective digestive decontamination regimen was associated with a lower ICU mortality rate and lower acquisition rates of pneumonia and bloodstream infection than the use of standard care alone. The favourable effect of infection prevention by selective digestive decontamination or selective oral decontamination regimens on mortality in ICU is controversial. In contrast, in European ICUs with intermediate or high level antimicrobial resistance, a selective digestive decontamination regimen without systemic antibiotics did not decreased mortality compared to other interventions (chlorhexidine mouthwash, selective oral decontamination) or standard care [[7]]. [Extracted from the article]