학술논문
High‐resolution fast‐tomography brain‐imaging beamline at the Taiwan Photon Source.
Document Type
Article
Author
Chen, Hsiang Hsin; Yang, Shun-Min; Yang, Kai-En; Chiu, Ching-Yu; Chang, Chia-Ju; Wang, Ya-Sian; Lee, Tsung-Tse; Huang, Yu-Fen; Chen, Yi-Yun; Petibois, Cyril; Chang, Shih-Hung; Cai, Xiaoqing; Low, Chian-Ming; Tan, Francis Chee Kuan; Teo, Alvin; Tok, Eng Soon; Lim, Jae-Hong; Je, Jun-Ho; Kohmura, Yoshiki; Ishikawa, Tetsuya
Source
Subject
*PHOTONS
*THREE-dimensional imaging
*BRAIN mapping
*BRAIN imaging
*X-rays
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Language
ISSN
0909-0495
Abstract
The new Brain Imaging Beamline (BIB) of the Taiwan Photon Source (TPS) has been commissioned and opened to users. The BIB and in particular its endstation are designed to take advantage of bright unmonochromatized synchrotron X‐rays and target fast 3D imaging, ∼1 ms exposure time plus very high ∼0.3 µm spatial resolution. A critical step in achieving the planned performances was the solution to the X‐ray induced damaging problems of the detection system. High‐energy photons were identified as their principal cause and were solved by combining tailored filters/attenuators and a high‐energy cut‐off mirror. This enabled the tomography acquisition throughput to reach >1 mm3 min−1, a critical performance for large‐animal brain mapping and a vital mission of the beamline. [ABSTRACT FROM AUTHOR]