학술논문

Validation of the Lee‐Jones theoretical model of fear of cancer recurrence among breast cancer survivors using a structural equation modeling approach.
Document Type
Article
Source
Psycho-Oncology. Feb2023, Vol. 32 Issue 2, p256-265. 10p. 1 Diagram, 2 Charts, 1 Graph.
Subject
*CANCER relapse
*STRUCTURAL equation modeling
*BREAST cancer
*CANCER survivors
*CLINICAL trial registries
Language
ISSN
1057-9249
Abstract
Objective: The Lee‐Jones model posits that antecedent individual and interpersonal factors predicate the development of fear of cancer recurrence (FCR) through cognitive and emotional processing, which further to behavioral, emotional, and/or physiological responses. We analyzed data from FoRtitude, a FCR intervention grounded in the Lee‐Jones FCR model, to evaluate associations between FCR antecedents, resources (e.g., breast cancer self‐efficacy, BCSE) and psychological and behavioral consequences. Methods: Women with breast cancer who completed treatment and reported clinically elevated levels of FCR were randomized into a 4‐week online psychosocial intervention or contact control group. We assessed BCSE, FCR, and physical activity, anxiety and depression, or symptoms at baseline, 4 and 8 weeks. Separate structural equation models were constructed with both baseline data and change scores (baseline‐8 weeks) to examine the pathways linking BCSE, FCR and: (1) physical activity; (2) anxiety and depression; and (3) symptoms (fatigue, sleep disturbance, cognitive concerns). Results: At baseline, higher levels of BCSE were associated with lower levels of FCR. Higher FCR was associated with worse psychological effects and symptoms but not behavioral response. Change models revealed that an increase in BCSE was associated with a decrease in FCR at 8‐week assessment, which was associated with reductions in psychological effects. A change in BCSE was also directly associated with reductions in psychological effects. Conclusions: Results support the Lee‐Jones model as a foundation for FCR interventions among breast cancer survivors. Replicability among varied populations is needed to examine effects on behavioral outcomes of FCR such as health care utilization. Clinical Trials Registration: NCT03384992. [ABSTRACT FROM AUTHOR]