학술논문
Remdesivir for the Prevention of Invasive Mechanical Ventilation or Death in Coronavirus Disease 2019 (COVID-19): A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data.
Document Type
Article
Author
Source
Subject
*THERAPEUTIC use of monoclonal antibodies
*STATISTICS
*DISEASE progression
*DRUG efficacy
*COVID-19
*OPERATIVE surgery
*RETROSPECTIVE studies
*ARTIFICIAL respiration
*TREATMENT effectiveness
*RISK assessment
*OXYGEN therapy
*DEATH
*DATA analysis
*LONGITUDINAL method
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Language
ISSN
1058-4838
Abstract
This post hoc analysis of the Adaptive Coronavirus Disease 2019 (COVID-19) Treatment Trial-1 (ACTT-1) shows a treatment effect of remdesivir (RDV) on progression to invasive mechanical ventilation (IMV) or death. Additionally, we create a risk profile that better predicts progression than baseline oxygen requirement alone. The highest risk group derives the greatest treatment effect from RDV. [ABSTRACT FROM AUTHOR]