학술논문

Synthesis of purine conjugates with N-(4-aminobenzenesulfonyl)-and N-(2-aminoethanesulfonyl)-(S)-glutamic acids.
Document Type
Article
Source
Russian Chemical Bulletin. Dec2022, Vol. 71 Issue 12, p2685-2690. 6p.
Subject
*GLUTAMIC acid
*ACIDS
Language
ISSN
1066-5285
Abstract
The approaches to the synthesis of purine conjugates with N-(4-aminobenzenesulfonyl)-(S)-glutamic acid and N-(2-ammoethanesulfonyl)-(S)-glutamic acid by nucleophilic substitution of chlorine atom in 6-chloropurine derivatives have been developed. The studied compounds did not show significant antimycobacterial activity in the in vitro experiment. [ABSTRACT FROM AUTHOR]