학술논문

Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenase.
Document Type
Article
Source
Nature. 6/24/1993, Vol. 363 Issue 6431, p693. 6p. 3 Color Photographs, 3 Diagrams, 1 Chart.
Subject
*ENZYMES
Language
ISSN
0028-0836
Abstract
Analyses the catalytic pathway in dehalogenase as a function of pH and temperature by high-resolution X-ray crystallography. Determining crystal structures of haloalkane dehalogenase through application of substrate 1,2-dichloroethane; Substrate binding; The alkyl-enzyme; Interactions of active site residues of dehalogenase, with substrate, before, during and after hydrolysis.