학술논문
Urinary tract infections, VUR, and autosomal dominant polycystic kidney disease.
Document Type
Article
Source
Subject
*POLYCYSTIC kidney disease
*URINARY tract infections
*PEDIATRIC radiology
*VESICO-ureteral reflux in children
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Language
ISSN
0931-041X
Abstract
This case series of 16 patients with autosomal dominant polycystic kidney disease (ADPKD) describes 4 girls who presented with a urinary tract infection (UTI). Radiological evaluation revealed that each of these patients had vesicoureteral reflux (VUR). The frequency of VUR was significantly higher in the patients with ADPKD compared with otherwise healthy age-matched children who underwent testing after a UTI (100% versus 15%, P<0.002). These findings suggest VUR is an associated somatic anomaly in children with ADPKD that may contribute to the occurrence of UTI in this patient population. [ABSTRACT FROM AUTHOR]