학술논문

BCRP drives intrinsic chemoresistance in chemotherapy-naïve breast cancer brain metastasis.
Document Type
Article
Source
Science Advances. 10/20/2023, Vol. 9 Issue 42, p1-17. 17p.
Subject
*BREAST
*ISOFLURANE
*DOXORUBICIN
*DRUG resistance in cancer cells
*PATHOLOGY
Language
ISSN
2375-2548
Abstract
The article focuses on understanding intrinsic chemoresistance in chemotherapy-naïve breast cancer brain metastasis. Topics discussed include the development of vascular mimicry in brain metastases and the role of the breast cancer resistance protein (BCRP) transporter in providing chemoresistance without prior chemotherapy exposure.